A review by researchers from the University of Birmingham and the University of Oxford in the UK has found that controlled doses of laughing gas (or nitrous oxide) really can provide quick-acting relief from depression.

The researchers found that administering the gas helped reduce depressive symptoms in as little as two hours. Relief was relatively short-lived, with symptoms returning within the week unless the dose was repeated.

“This study brings together the best possible evidence indicating that nitrous oxide has the potential to provide swift and clinically significant short-term improvements in patients with severe depression,” says clinical psychologist Kiranpreet Gill, from the University of Birmingham.

  • Icytrees@sh.itjust.worksOPM
    1·
    10 days ago

    I was too tired when I wrote that. Vortiexone is my nothing burger. Wellbutrin has no noticable effect for me on it’s own and ramps up my anxiety if I’m on other stimulants.

    I haven’t looked at the clinical depression treatment doses of the cold meds turned brain meds yet, but maybe? It’s already a psych drug anyway that targets that reflex.

    I make a point of not looking up drugs I’m trying, I take notes instead and compare later with my psyche. Right now it’s a mix of Adderall, duloxetine and abilify, which work pretty well for me as a triad but none of them do much for me individually, even 20mg of adderall is like a couple coffees.

    Brains are fucking weird.

    You know those hipster Speakeasy’s with some prodigal bartender who mixes your favorite drink? I imagine there’s one of those somewhere with a mustachio’d psychopharmacologist in a rustic leather apron, who takes one look at you before he starts tossing ingredients into a mortar, with flourishes and puns. He’s got a vintage copper pill press that spins on a motor, flinging tablets he catches in a green glass bottle, pops the cork stopper and hands you your ~perfect drug~